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Cayman I-SAP
List Price
$633.00
Your Price
$633.00
Cayman I-SAP - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-19021-1
MFG.PART:
19021-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
I-SAP is a high affinity TP receptor antagonist. At physiologic pH, I-SAP produces platelet shape change, but not aggregation, with an EC50 value of 9.7 nM. I-SAP binds to human platelets with the maximum binding obtained between pH 6.5 and pH 7.4. In washed human platelets, the Kd for I-SAP is 468 pM at pH 7.4 and 490 pM at pH 6.5.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(5Z)-7-[(1S, 2S,3S,5R)-3- [[(4-iodo phenyl) sulfonyl] amino]-6,6- dimethylbicyclo [3.1.1]hept- 2-yl]-5- heptenoic acid
CAS Number
133538-58-6
Synonyms
- Iodophenyl sulfonyl amino pinane Thromboxane A2
- Iodophenyl sulfonyl amino pinane TXA2
Molecular Formula
C22H30INO4S
Formula Weight
531.4
Purity
≥98%
Formulation
A solution in ethanol
Solubility
- DMF: >50 mg/mL (from Pinane TXA2)
- DMSO: >25 mg/mL (from Pinane TXA2)
- Ethanol: >100 mg/mL (from Pinane TXA2)
- PBS pH 7.2: >100 µg/mL (from Pinane TXA2)
λmax
249 nm
SMILES
CC1(C)[C@@H]2[C@H](C/C=C\CCCC(O)=O)[C@@H](N([H])S(C3=CC=C(I)C=C3)(=O)=O)C[C@H]1C2
InChi Code
InChI=1S/C22H30INO4S/c1-22(2)15-13-19(22)18(7-5-3-4-6-8-21(25)26)20(14-15)24-29(27,28)17-11-9-16(23)10-12-17/h3,5,9-12,15,18-20,24H,4,6-8,13-14H2,1-2H3,(H,25,26)/b5-3-/t15-,18+,19+,20+/m1/s1
InChi Key
SZNMERGTFJHNSM-JAWYFFTGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-19021-1 |
|---|---|
| Supplier Part Number | 19021-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 133538-58-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |