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Cayman Cl 387,785; Purity- Greater Than Or Equal To 95%; Size- 10
List Price
$178.00
Your Price
$178.00
Cayman Cl 387,785; Purity- Greater Than Or Equal To 95%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-19081-10
MFG.PART:
19081-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Cinacalcet-d3 is intended for use as an internal standard for the quantification of cinacalcet (Item No. ) by GC- or LC-MS. Cinacalcet is a calcimimetic and an allosteric agonist of the calcium-sensing receptor (CaSR; EC50 = 79.4 nM in HEK293T cells expressing the human receptor). In vivo, cinacalcet (0.1-10 mg/kg, s.c.) decreases plasma levels of parathyroid hormone (PTH) in rats. It also decreases plasma levels of PTH and parathyroid cell proliferation in a mouse model of primary hyperparathyroidism. Formulations containing cinacalcet have been used in the treatment of secondary hyperparathyroidism due to end-stage renal disease and hypercalcemia in patients with parathyroid carcinoma.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(αR)-
CAS Number
2749807-20-1
Synonyms
- AMG 073-d3
Molecular Formula
C22H19D3F3N • HCl
Formula Weight
396.9
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solid
Solubility
- DMF: Soluble
- DMSO: Soluble
- Ethanol: Soluble
- Methanol: Soluble
SMILES
[2H]C([2H])([2H])[C@@H](NCCCC1=CC(C(F)(F)F)=CC=C1)C2=CC=CC3=C2C=CC=C3.Cl
InChi Code
InChI=1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m1./s1/i1D3;
InChi Key
QANQWUQOEJZMLL-GFGUQVGFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19081-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 19081-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 194423-06-8 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |