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Cayman LLP-3
List Price
$96.00
Your Price
$96.00
Cayman LLP-3 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-19088-1
MFG.PART:
19088-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Survivin (also known as baculoviral IAP repeat-containing protein 5 (BIRC5)) is a member of the inhibitor of apoptosis (IAP) family that interacts with and inhibits the apoptotic function of several proteins., LLP-3 is a cell-permeable ligand of Survivin that blocks its interaction with Ran, resulting in the induction of apoptosis (IAP) in glioma stem cells (IC50 = 31 µM). It abolishes the growth of glioblastoma multiforme cell in spheres and in tumor slice cultures.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[3,5-bis
CAS Number
1453835-43-2
Molecular Formula
C32H23ClN2O4
Formula Weight
535.0
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 2 mg/mL
- DMF:PBS(pH7.2) (1:2): 0.3 mg/mL
- DMSO: 2 mg/mL
λmax
372 nm
SMILES
O=C1NC(C2=C(O)C=CC(Cl)=C2)=CC(C3=CC(OCC4=CC=CC=C4)=CC(OCC5=CC=CC=C5)=C3)=C1C#N
InChi Code
InChI=1S/C32H23ClN2O4/c33-24-11-12-31(36)28(15-24)30-17-27(29(18-34)32(37)35-30)23-13-25(38-19-21-7-3-1-4-8-21)16-26(14-23)39-20-22-9-5-2-6-10-22/h1-17,36H,19-20H2,(H,35,37)
InChi Key
NZRBRJQYGLEINZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19088-1 |
|---|---|
| Supplier Part Number | 19088-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1453835-43-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |