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Cayman TY 52156
List Price $462.00 Your Price $462.00
Cayman TY 52156 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-19119-25
MFG.PART: 19119-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
TY 52156 is a selective sphingosine-1-phosphate receptor 3 (SIP3) antagonist (Ki = 110 nM).1 It preferentially inhibits the S1P-induced increase in intracellular calcium in Chinese hamster ovary cells expressing S1P3 over cell expressing S1P1, S1P2, or S1P4.1 TY 52156 has been shown to suppress FTY720-induced S1P3 receptor-mediated coronary flow in isolated perfused rat hearts.1 TY 52156 can also inhibit S1P-induced breast cancer stem cell expansion in vitro.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-
CAS Number
934369-14-9
Molecular Formula
C18H19Cl2N3O
Formula Weight
364.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 25 mg/mL
- Ethanol: 15 mg/mL
λmax
248, 301, 359 nm
SMILES
CC(C)(C)C(/C(NNC1=CC=C(Cl)C=C1)=N/C2=CC=C(Cl)C=C2)=O
InChi Code
InChI=1S/C18H19Cl2N3O/c1-18(2,3)16(24)17(21-14-8-4-12(19)5-9-14)23-22-15-10-6-13(20)7-11-15/h4-11,22H,1-3H3,(H,21,23)
InChi Key
XONRRGIRSGNWFP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19119-25 |
|---|---|
| Supplier Part Number | 19119-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 934369-14-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |