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Cayman NK 252
List Price
$36.00
Your Price
$36.00
Cayman NK 252 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-19131-1
MFG.PART:
19131-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
NK 252 is a Nrf2 activator that interacts directly with the domain containing the Nrf2-binding site of Keap1. At 1.36 µM, it is reported to activate the NQO1-antioxidant response element in a luciferase reporter gene assay two-fold above background. NK 252 has been shown to downregulate the expression of fibrogenic genes, producing antifibrotic effects in a rat model of non-alcoholic steatohepatitis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[5-
CAS Number
1414963-82-8
Molecular Formula
C13H11N5O3
Formula Weight
285.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL
- DMSO: 14 mg/mL
λmax
275 nm
SMILES
O=C(NC1=NN=C(C2=CC=CO2)O1)NCC3=CC=CC=N3
InChi Code
InChI=1S/C13H11N5O3/c19-12(15-8-9-4-1-2-6-14-9)16-13-18-17-11(21-13)10-5-3-7-20-10/h1-7H,8H2,(H2,15,16,18,19)
InChi Key
FNSCFQXZZNCDAI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19131-1 |
|---|---|
| Supplier Part Number | 19131-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1414963-82-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |