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Cayman Mps1-IN-1
List Price
$71.00
Your Price
$71.00
Cayman Mps1-IN-1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-19175-1
MFG.PART:
19175-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Mps1-IN-1 is a selective inhibitor of monopolar spindle 1 (Mps1) kinase (IC50 = 367 nM), a dual-specificity kinase involved in spindle assembly checkpoint and the maintenance of chromosomal stability. It exhibits greater than 1,000-fold selectivity against a panel of 352 kinases. Mps1-IN-1 has been shown to disrupt the recruitment of Mad2 to kinetochores and to increase the frequency of multipolar mitosis in U2OS cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-
CAS Number
1125593-20-5
Synonyms
- Monopolar Spindle 1 Kinase Inhibitor 1
- Mps1 Kinase Inhibitor 1
Molecular Formula
C28H33N5O4S
Formula Weight
535.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 50 mg/mL
- DMF:PBS (pH 7.2) (1:9): 0.1 mg/mL
- DMSO: 30 mg/mL
λmax
295 nm
SMILES
COC1=C(NC2=CC(NC3=CC=CC=C3S(C(C)C)(=O)=O)=C(C=CN4)C4=N2)C=CC(N5CCC(O)CC5)=C1
InChi Code
InChI=1S/C28H33N5O4S/c1-18(2)38(35,36)26-7-5-4-6-23(26)30-24-17-27(32-28-21(24)10-13-29-28)31-22-9-8-19(16-25(22)37-3)33-14-11-20(34)12-15-33/h4-10,13,16-18,20,34H,11-12,14-15H2,1-3H3,(H3,29,30,31,32)
InChi Key
NMJMRSQTDLRCRQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19175-1 |
|---|---|
| Supplier Part Number | 19175-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1125593-20-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |