Cayman Ver-246608; Qty- 1; Size-1 Mg

Precocene II is a chromene that has been found in A. houstonianum and has anti-juvenile hormone activity.^,, It inhibits juvenile hormone biosynthesis in isolated spontaneously active cockroach (P. americana) corpora allata when used at concentrations of 1 mM or higher. Precocene II (8 μg/cm² coating in Petri dish) inhibits development of the corpus allatum in newly eclosed female milkweed bugs and causes allatal regression when applied 120 hours post-eclosion in normally developing females. It induces precocious metamorphosis in milkweed bug second-stage nymphs when applied as a coating to Petri dishes at concentrations of 0.4 and 0.7 μg/cm². Precocene II inhibits ovarian development in various insects, including milkweed bugs, cotton stainers, apple maggots, and Mexican bean beetles. Precocene II also inhibits production of the trichothecene mycotoxin 3-acetyldeoxy nivalenol (3-ADON; Item No. ) in F. graminearum (IC₅₀ = 1.2 μM) without inhibiting fungal growth.

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