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Cayman Nimbolide
List Price $1,164.00 Your Price $1,164.00
Cayman Nimbolide - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-19230-25
MFG.PART: 19230-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Nimbolide is a terpenoid lactone first isolated from A. indica (Neem tree) that demonstrates antimalarial and anticancer effects in experimental models. It inhibits pancreatic cancer cell growth and metastasis by inducing the excessive generation of ROS, reducing PI3K/Akt/mTOR and ERK signaling, and upregulating the pro-apoptotic proteins Bax, caspase-3, and PARP.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
8-(3-furanyl)
CAS Number
25990-37-8
Synonyms
- NSC 309909
Molecular Formula
C27H30O7
Formula Weight
466.5
Purity
≥97%
Formulation
A crystalline solid
Solubility
- DMF: 12 mg/mL
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL
- DMSO: 11 mg/mL
λmax
213 nm
SMILES
CC1=C2[C@](CC1C3=COC=C3)([H])O[C@]([C@]2(C)[C@@H]4CC(OC)=O)([H])[C@@]5([H])C6[C@]4(C)C(C=C[C@@]6(C)C(O5)=O)=O
InChi Code
InChI=1S/C27H30O7/c1-13-15(14-7-9-32-12-14)10-16-20(13)27(4)17(11-19(29)31-5)26(3)18(28)6-8-25(2)22(26)21(23(27)33-16)34-24(25)30/h6-9,12,15-17,21-23H,10-11H2,1-5H3/t15?,16-,17-,21-,22?,23-,25-,26+,27-/m1/s1
InChi Key
JZIQWNPPBKFOPT-FTCZZEDLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-19230-25 |
|---|---|
| Supplier Part Number | 19230-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 25990-37-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |