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Cayman UNC3866
List Price $53.00 Your Price $53.00
Cayman UNC3866 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-19237-1
MFG.PART: 19237-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
UNC3866 is an inhibitor of chromobox homolog 7 (CBX7; Kd = 97 nM). It also binds to CBX4 (Kd = 94 nM) but is greater than 6-fold selective over CBX2, 6, and 8 and the chromodomain Y family (CDY) chromodomains CDY1, L1b, and L2 (Kds = 0.61-6.3 μM). UNC3866 pretreatment (30 μM) of PC3 lysates completely inhibits chemiprecipitation of CBX7. It induces a senescent-like morphology and reduces growth of PC3 cells with an EC50 value of 7.6 μM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[4-(1,1-di
CAS Number
1872382-47-2
Molecular Formula
C43H66N6O8
Formula Weight
795.0
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 33 mg/mL
- DMSO: 33 mg/mL
- DMSO:PBS(pH 7.2) (1:4): 0.2 mg/mL
- Ethanol: 16 mg/mL
λmax
240 nm
SMILES
CC(C)(C1=CC=C(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(OC)=O)CO)=O)CCCCN(CC)CC)=O)CC(C)C)=O)C)=O)CC2=CC=CC=C2)=O)C=C1)C
InChi Code
InChI=1S/C43H66N6O8/c1-10-49(11-2)24-16-15-19-33(39(53)48-36(27-50)42(56)57-9)45-41(55)34(25-28(3)4)46-37(51)29(5)44-40(54)35(26-30-17-13-12-14-18-30)47-38(52)31-20-22-32(23-21-31)43(6,7)8/h12-14,17-18,20-23,28-29,33-36,50H,10-11,15-16,19,24-27H2,1-9
InChi Key
UMRRDXVUROEIKJ-JCXBGQGISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19237-1 |
|---|---|
| Supplier Part Number | 19237-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1872382-47-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |