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Cayman (S)-p38 MAPK Inhibitor III
List Price $143.00 Your Price $143.00
Cayman (S)-p38 MAPK Inhibitor III - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-19696-1
MFG.PART: 19696-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 µM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 µM, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[5-(4-
CAS Number
581098-48-8
Synonyms
- (S)-p38 MAP Kinase Inhibitor III
- (S)-p38 Mitogen-activated Protein Kinase Inhibitor III
Molecular Formula
C23H21FN4S
Formula Weight
404.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMSO: 12 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/mL
λmax
253, 304 nm
SMILES
FC1=CC=C(C2=C(C3=CC=NC(N[C@@H](C)C4=CC=CC=C4)=C3)N=C(SC)N2)C=C1
InChi Code
InChI=1S/C23H21FN4S/c1-15(16-6-4-3-5-7-16)26-20-14-18(12-13-25-20)22-21(27-23(28-22)29-2)17-8-10-19(24)11-9-17/h3-15H,1-2H3,(H,25,26)(H,27,28)/t15-/m0/s1
InChi Key
VXPWQNBKEIVYIS-HNNXBMFYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-19696-1 |
|---|---|
| Supplier Part Number | 19696-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 581098-48-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |