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Cayman BMN 673
List Price $80.00 Your Price $80.00
Cayman BMN 673 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-19782-1
MFG.PART: 19782-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
BMN 673 is an orally available poly(ADP-ribose) polymerase (PARP) inhibitor with an IC50 value of 0.57 nM. It similarly binds to PARP1 and PARP2 with Ki values of 1.2 and 0.85 nM, respectively, but has no effect on PARG. BMN 673 selectively targets tumor cells with BRCA1, BRCA2, or PTEN gene mutations and elicits antitumor activity in xenografted tumors in mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(8S,9R)-5-
CAS Number
1207456-01-6
Synonyms
- Talazoparib
Molecular Formula
C19H14F2N6O
Formula Weight
380.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/mL
- DMF:PBS (pH 7.2)(1:3): 0.25 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 0.25 mg/mL
λmax
255, 309 nm
SMILES
O=C1NN=C2[C@H](C3=NC=NN3C)[C@@H](C4=CC=C(F)C=C4)NC5=C2C1=CC(F)=C5
InChi Code
InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,24H,1H3,(H,26,28)/t15-,16-/m1/s1
InChi Key
HWGQMRYQVZSGDQ-HZPDHXFCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19782-1 |
|---|---|
| Supplier Part Number | 19782-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1207456-01-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |