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Cayman AZ 6102
List Price $583.00 Your Price $583.00
Cayman AZ 6102 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-19898-25
MFG.PART: 19898-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
AZ 6102 is an inhibitor of tankyrases (TNKS) 1 and 2 with IC50 values of 3 and 1 nM, respectively.1 It demonstrates 100-fold selectivity for TNKS1/2 over PARP1, PARP2, and PARP6 (IC50s = 2, 0.5, and >3 µM, respectively).1 By inhibiting TNKS1/2, AZ6120 has been shown to inhibit Wnt signaling in DLD-1 cells with an IC50 value of 5 nM.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
rel-2-[4-[6-[
CAS Number
1645286-75-4
Molecular Formula
C25H28N6O
Formula Weight
428.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 15 mg/mL
- DMF:PBS(pH7.2) (1:2): 0.3 mg/mL
- DMSO: 10 mg/mL
λmax
327 nm
SMILES
C[C@H]1CN(C2=NC=C(C3=CC=C(C4=NC(C(C=CN5C)=C5N4)=O)C=C3)C(C)=C2)C[C@@H](C)N1
InChi Code
InChI=1S/C25H28N6O/c1-15-11-22(31-13-16(2)27-17(3)14-31)26-12-21(15)18-5-7-19(8-6-18)23-28-24-20(25(32)29-23)9-10-30(24)4/h5-12,16-17,27H,13-14H2,1-4H3,(H,28,29,32)/t16-,17+
InChi Key
WCPTUQOMNJBIET-CALCHBBNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19898-25 |
|---|---|
| Supplier Part Number | 19898-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1645286-75-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |