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Cayman AP-III-a4
List Price
$79.00
Your Price
$79.00
Cayman AP-III-a4 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-19933-1
MFG.PART:
19933-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
AP-III-a4 is a small molecule enolase inhibitor (IC50 = 0.576 µM) that inhibited cancer cell metastasis in an in vivo zebrafish cancer cell xenograft model. It also reduced hyperglycemia and hyperlipidemia in C57BL/Ksj-db/db mice, a transgenic model of type 2 diabetes. Another study found that AP-III-a4 did not directly block enolase activity in vitro and suggested the mechanism is indirect.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[2-[2-(2-
CAS Number
1177827-73-4
Synonyms
- ENOblock
Molecular Formula
C31H43FN8O3
Formula Weight
594.7
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/mL
λmax
211, 268 nm
SMILES
FC(C=C1)=CC=C1CNC2=NC(NC3=CC=C(CC(NCCOCCOCCN)=O)C=C3)=NC(NCC4CCCCC4)=N2
InChi Code
InChI=1S/C31H43FN8O3/c32-26-10-6-25(7-11-26)22-36-30-38-29(35-21-24-4-2-1-3-5-24)39-31(40-30)37-27-12-8-23(9-13-27)20-28(41)34-15-17-43-19-18-42-16-14-33/h6-13,24H,1-5,14-22,33H2,(H,34,41)(H3,35,36,37,38,39,40)
InChi Key
MOVYITHKOHMLHC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19933-1 |
|---|---|
| Supplier Part Number | 19933-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1177827-73-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |