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Cayman CC-885
List Price
$189.00
Your Price
$189.00
Cayman CC-885 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-19966-1
MFG.PART:
19966-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
CC-885 is a modulator of the E3 ligase protein cereblon with antiproliferative effects on human myeloid leukemia cell lines. It forms a complex with cereblon and the cell cycle regulator and translation termination factor GSPT1. The antitumour activity of CC-885 relies on cereblon-dependent ubiquitination and degradation of the GSPT1.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(3-chloro-
CAS Number
1010100-07-8
Molecular Formula
C22H21ClN4O4
Formula Weight
440.9
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 12.5 mg/mL
- DMSO: 12.5 mg/mL
- DMSO:PBS(pH 7.2) (1:4): 0.2 mg/mL
λmax
244 nm
SMILES
O=C1NC(CCC1N2C(C(C=CC(CNC(NC3=CC(Cl)=C(C)C=C3)=O)=C4)=C4C2)=O)=O
InChi Code
InChI=1S/C22H21ClN4O4/c1-12-2-4-15(9-17(12)23)25-22(31)24-10-13-3-5-16-14(8-13)11-27(21(16)30)18-6-7-19(28)26-20(18)29/h2-5,8-9,18H,6-7,10-11H2,1H3,(H2,24,25,31)(H,26,28,29)
InChi Key
DOEVCIHTTTYVCC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-19966-1 |
|---|---|
| Supplier Part Number | 19966-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1010100-07-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |