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Cayman Rotigotine
List Price $120.00 Your Price $120.00
Cayman Rotigotine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-20246-10
MFG.PART: 20246-10
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
Rotigotine is a non-selective dopamine receptor agonist with pEC50 values of 9.6, 10.4, 8.2, 7.7, and 7.7 for D1, D2, D3, D4, and D5, respectively.1 It demonstrates a high-affinity for D1, D2, and D3 with lesser affinity for D4 and D5 receptor subtypes.1 This binding profile is similar to that of apomorphine (Item No. 16094) and pergolide but differentiated from that of pramipexole (Item No. 11981) and ropinirole, which have a more narrow profile of receptor specificity.1 Each of these agonists demonstrates anti-Parkinsonian effects in animal and clinical models through their ability to directly activate dopamine receptors.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(6S)-5,6,7,8- tetrahydro-6- [propyl[2-(2- thienyl) ethyl]amino]- 1-naphthalenol
CAS Number
99755-59-6
Synonyms
- N-0923
- SPM 962
Molecular Formula
C19H25NOS
Formula Weight
315.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMF:PBS(pH7.2) (1:2): 0.33 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 1 mg/mL
λmax
224, 272 nm
SMILES
OC1=C(CC[C@H](N(CCC2=CC=CS2)CCC)C3)C3=CC=C1
InChi Code
InChI=1S/C19H25NOS/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21/h3-7,13,16,21H,2,8-12,14H2,1H3/t16-/m0/s1
InChi Key
KFQYTPMOWPVWEJ-INIZCTEOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-20246-10 |
|---|---|
| Supplier Part Number | 20246-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 99755-59-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |

