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Cayman Cholic Acid
List Price $101.00 Your Price $101.00
Cayman Cholic Acid - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-20250-100
MFG.PART: 20250-100
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA; Item No. ) and taurocholic acid (TCA; Item No. ), respectively, in the liver, and is transformed into the secondary bile acid deoxycholic acid (DCA; Item No. ) by intestinal microbiota.,, It induces C. difficile colony formation in an agar dilution assay when used at a concentration of 0.1% w/v. Dietary administration of cholic acid (0.4% w/w) increases serum cholesterol levels, biliary phospholipid secretion, and fecal DCA levels in rats.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(5β)-3α,7α,12
CAS Number
81-25-4
Synonyms
- Cholalic Acid
- Cholalin
- NSC 6135
Molecular Formula
C24H40O5
Formula Weight
408.6
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 1 mg/mL
- DMSO: 0.3 mg/mL
- PBS (pH 7.2): 1 mg/mL
SMILES
C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@@]21C
InChi Code
InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1
InChi Key
BHQCQFFYRZLCQQ-OELDTZBJSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-20250-100 |
|---|---|
| Supplier Part Number | 20250-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | 22 |
| Refrigerated-Frozen | N |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 81-25-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |