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Cayman Lithocholic Acid
List Price $66.00 Your Price $66.00
Cayman Lithocholic Acid - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-20253-10
MFG.PART: 20253-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Lithocholic acid is a secondary bile acid that has been shown to cause cholestasis in animal models and has also been implicated in carcinogenesis., It is produced from chenodeoxycholic acid by bacterial action in the colon and can be conjugated with glycine or taurine. Whereas in normal colonic epithelium lithocholic acid promotes apoptosis, it has been shown to suppress apoptosis in pre-malignant colonic epithelium in the presence of a carcinogen. Lithocholic acid can activate the pregnane X receptor and the vitamin D receptor, which may serve as a biological sensor to regulate lithocholic acid-induced toxicity.,,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3α,5β)-3-
CAS Number
434-13-9
Synonyms
- 3α-hydroxy Cholanic Acid
- LCA
- Lithocholate
- NSC 683770
Molecular Formula
C24H40O3
Formula Weight
376.6
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMF:PBS (pH 7.2) (1:1): 0.5 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 20 mg/mL
SMILES
C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1
InChi Key
SMEROWZSTRWXGI-HVATVPOCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-20253-10 |
|---|---|
| Supplier Part Number | 20253-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 434-13-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |