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Cayman Tauro-β-muricholic Acid (sodium salt)
List Price $472.00 Your Price $472.00
Cayman Tauro-β-muricholic Acid (sodium salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-20289-5
MFG.PART: 20289-5
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Tauro-β-muricholic acid (TβMCA) is a competitive and reversible antagonist of the farnesoid X receptor (FXR; IC50 = 40 µM) and a taurine-conjugated form of the murine-specific primary bile acid β-muricholic acid (Item No. 20287).1 TβMCA accumulates in germ-free mice under normal conditions but is reduced after colonization with feces from a human donor.1,2 TβMCA is increased in the intestines of mice resistant to high-fat diet-induced obesity, fatty liver, and diabetes.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[(3α,5β,
CAS Number
145022-92-0
Synonyms
- Tauro-β-muricholate
- TβMCA
Molecular Formula
C26H44NO7S • Na
Formula Weight
537.7
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 10 mg/mL
- DMSO:PBS(pH 7.2) (1:4): 0.1 mg/mL
- Ethanol: 1 mg/mL
SMILES
C[C@H](CCC(NCCS([O-])(=O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)[C@@H](O)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C.[Na+]
InChi Code
InChI=1S/C26H45NO7S.Na/c1-15(4-7-21(29)27-12-13-35(32,33)34)17-5-6-18-22-19(9-11-25(17,18)2)26(3)10-8-16(28)14-20(26)23(30)24(22)31;/h15-20,22-24,28,30-31H,4-14H2,1-3H3,(H,27,29)(H,32,33,34);/q;+1/p-1/t15-,16-,17-,18+,19+,20+,22+,23+,24-,25-,26-;/m1./s1
InChi Key
NYXROOLWUZIWRB-GPHZYVDLSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-20289-5 |
|---|---|
| Supplier Part Number | 20289-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 145022-92-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |