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Cayman Ketotifen (fumarate)
List Price $79.00 Your Price $79.00
Cayman Ketotifen (fumarate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-20303-1
MFG.PART: 20303-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Ketotifen is a histamine H1 receptor antagonist (Ki = 1.3 nM) and mast cell stabilizer., It is selective for H1 receptors over H2 and H3 receptors (Kis = 987 and 2,500 nM, respectively). Ketotifen (50 and 100 μM) inhibits degranulation of rat peritoneal mast cells induced by compound 48/80 (Item No. ). It inhibits the passive cutaneous anaphylaxis (PCA) reaction in rats by 54.6% when administered orally at a dose of 20 mg/kg. Ketotifen (30 mg/kg) inhibits the quick phase airway response in a rat ovalbumin-induced immediate airway response model. Formulations containing ketotifen have been used in the treatment of itching associated with allergic conjunctivitis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4,9-dihydro-
CAS Number
34580-14-8
Synonyms
- HC 20511
Molecular Formula
C19H19NOS • C4H4O4
Formula Weight
425.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/mL
- DMSO: 25 mg/mL
- DMSO:PBS(pH 7.2) (1:2): .3 mg/mL
- Ethanol: .5 mg/mL
λmax
250, 309 nm
SMILES
O=C1C2=C(C=CS2)/C(C3=CC=CC=C3C1)=C4CCN(C)CC/4.OC(/C=C/C(O)=O)=O
InChi Code
InChI=1S/C19H19NOS.C4H4O4/c1-20-9-6-13(7-10-20)18-15-5-3-2-4-14(15)12-17(21)19-16(18)8-11-22-19;5-3(6)1-2-4(7)8/h2-5,8,11H,6-7,9-10,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
InChi Key
YNQQEYBLVYAWNX-WLHGVMLRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-20303-1 |
|---|---|
| Supplier Part Number | 20303-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 34580-14-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |