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Cayman Fura-FF AM
List Price
$70.00
Your Price
$70.00
Cayman Fura-FF AM - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-20416-50
MFG.PART:
20416-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Fura-FF AM is a cell-permeable acetoxymethyl ester of the fluorescence calcium indicator fura-FF (potassium salt) (Item No. ). As fura-FF AM enters cells, it is hydrolyzed by intracellular esterases to produce fura-FF. Fura-FF is a difluorinated derivative of the calcium indicator fura-2 (Item Nos. | ). Unlike, fura-2, fura-FF has negligible magnesium sensitivity, thus reducing interference from this cation. Fura-FF also has a higher calcium dissociation constant than fura-2 (Kd(calcium) = 6 and 0.14 µM, respectively)., However, the spectral properties of fura-FF and fura-2 are similar with fura-FF displaying excitation/emission spectra of 365/514 nm in the absence of calcium, with a shift to 339/507 nm in the presence of a high calcium concentration. Low affinity calcium dyes, including fura-FF, are preferred for studying compartments with high concentrations of calcium, such as mitochondria, or in cell systems that have relatively low calcium buffering capacities, such as neuronal dendrites and spines.,,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[6-[bis[2-
CAS Number
348079-12-9
Synonyms
- Fura-FF Acetoxymethyl ester
Molecular Formula
C43H43F2N3O24
Formula Weight
1023.8
Purity
≥90%
Emission
514 nm (no Ca2+), 507 nm (high [Ca2+])
Excitation
365 nm (no Ca2+), 339 nm (high [Ca2+])
Formulation
A solid
Solubility
- DMSO: soluble
SMILES
O=C(OCOC(C)=O)CN(C1=CC2=C(C=C(C3=NC=C(C(OCOC(C)=O)=O)O3)O2)C=C1OCCOC(C(F)=C(F)C=C4)=C4N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O
InChi Code
InChI=1S/C43H43F2N3O24/c1-23(49)61-18-66-36(54)14-47(15-37(55)67-19-62-24(2)50)30-7-6-29(44)40(45)41(30)60-9-8-59-33-10-28-11-34(42-46-13-35(72-42)43(58)70-22-65-27(5)53)71-32(28)12-31(33)48(16-38(56)68-20-63-25(3)51)17-39(57)69-21-64-26(4)52/h6-7,10
InChi Key
FPUWXSBNYDMTRN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-20416-50 |
|---|---|
| Supplier Part Number | 20416-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 348079-12-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |