Cayman HT-2 Toxin

HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin (Item No. ).^, Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants. HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC₅₀ values ranging from 3.1 to 23 ng/mL and human umbilical vein endothelial cells (HUVECs) with an IC₅₀ value of 56.4 ng/mL. It induces oxidative stress, DNA damage, and autophagy in, as well as halts the development of, cultured mouse embryos when used at a concentration of 10 nM. HT-2 toxin has been found in cereal grains and food products.^,

WARNING This product is not for human or veterinary use.