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Cayman Necrosulfonamide
List Price $82.00 Your Price $82.00
Cayman Necrosulfonamide - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-20844-10
MFG.PART: 20844-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Necrosulfonamide is a small molecule that inhibits necroptosis by blocking mixed lineage kinase domain-like protein (MLKL), a key substrate of receptor-interacting serine-threonine kinase 3 (RIPK3). Necrosulfonamide has been shown to prevent the MLKL-RIPK1-RIPK3 necrosome complex from interacting with downstream necrosis effectors.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2E)-N-[4-[[
CAS Number
1360614-48-7
Molecular Formula
C18H15N5O6S2
Formula Weight
461.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/mL
- DMF:PBS (pH 7.2) (1:50): 0.5 mg/mL
- DMSO: 20 mg/mL
λmax
277, 366 nm
SMILES
O=S(C1=CC=C(NC(/C=C/C2=CC=C([N+]([O-])=O)S2)=O)C=C1)(NC3=C(OC)N=CC=N3)=O
InChi Code
InChI=1S/C18H15N5O6S2/c1-29-18-17(19-10-11-20-18)22-31(27,28)14-6-2-12(3-7-14)21-15(24)8-4-13-5-9-16(30-13)23(25)26/h2-11H,1H3,(H,19,22)(H,21,24)/b8-4+
InChi Key
FNPPHVLYVGMZMZ-XBXARRHUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-20844-10 |
|---|---|
| Supplier Part Number | 20844-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1360614-48-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |