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Cayman Dihydrocytochalasin B
List Price
$162.00
Your Price
$162.00
Cayman Dihydrocytochalasin B - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-20845-1
MFG.PART:
20845-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Dihydrocytochalasin B (DCB) is a member of the cytochalasin mycotoxin family that inhibits actin assembly. It blocks cleavage furrow formation and cytokinesis in synchronous HeLa cells at a concentration of 10 μM. DCB induces tetraploidy and arrests the cell cycle indefinitely in the g1 phase in REF-52 cells. It also increases the drug sensitivity of multidrug resistant SKVLB1 cells to paclitaxel (Item No. ) and doxorubicin (Item No. ) in vitro.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(5R,9R,11E,
CAS Number
39156-67-7
Synonyms
- DCB
Molecular Formula
C29H39NO5
Formula Weight
481.6
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMF:PBS (pH 7.2) (1:20): 0.05 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 20 mg/mL
SMILES
O=C1CC[C@H](O)CCC[C@@H](C)C/C=C/[C@]([C@H](O)C([C@@H](C)[C@@]2([H])[C@H](CC3=CC=CC=C3)NC4=O)=C)([H])[C@@]24O1
InChi Code
InChI=1S/C29H39NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14,18-19,22-24,26-27,31,33H,3,7,9-10,13,15-17H2,1-2H3,(H,30,34)/b14-8+/t18-,19-,22-,23+,24+,26+,27-,29-/m1/s1
InChi Key
WIULKAASLBZREV-RXPQEOCGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-20845-1 |
|---|---|
| Supplier Part Number | 20845-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Israel |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 39156-67-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |