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Cayman AZD 5153
List Price $322.00 Your Price $322.00
Cayman AZD 5153 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-20864-10
MFG.PART: 20864-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
AZD 5153 an orally available, bivalent inhibitor of the bromodomain and extraterminal (BET) protein BRD4 (IC50 = 5 nM).1 It can simultaneously bind two bromodomains in BRD4, which has been shown to increase antitumor activity in multiple xenograft models of acute myeloid leukemia, multiple myeloma, and diffuse large B cell lymphoma.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3R)-4-[2-[4-
CAS Number
1869912-39-9
Molecular Formula
C25H33N7O3
Formula Weight
479.6
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 20 mg/mL
- PBS (pH 7.2): 10 mg/mL
λmax
239, 283, 303 nm
SMILES
COC1=NN=C2N1N=C(N3CCC(C4=CC=C(OCCN5[C@H](C)C(N(C)CC5)=O)C=C4)CC3)C=C2
InChi Code
InChI=1S/C25H33N7O3/c1-18-24(33)29(2)14-15-30(18)16-17-35-21-6-4-19(5-7-21)20-10-12-31(13-11-20)23-9-8-22-26-27-25(34-3)32(22)28-23/h4-9,18,20H,10-17H2,1-3H3/t18-/m1/s1
InChi Key
RSMYFSPOTCDHHJ-GOSISDBHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-20864-10 |
|---|---|
| Supplier Part Number | 20864-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1869912-39-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |