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Cayman CRT0273750
List Price $610.00 Your Price $610.00
Cayman CRT0273750 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-20904-25
MFG.PART: 20904-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
CRT0273750 is an ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2) inhibitor (IC50 = 1 nM).1 It prevents lysophosphatidylcholine hydrolysis in a plasma choline release assay (IC50 = 13 nM). CRT0273750 inhibits the migration of 4T1 cells in a migration assay (IC50 = 24 nM). It decreases plasma levels of the ENPP2 hydrolysis product lysophosphatidic acid in an MDA-MB-231 mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(1S)-1-(4-chlorophenyl)ethyl]-3-[[4-(trifluoromethoxy)phenyl]methyl]-3H-imidazo[4,5-b]pyridine-2-propanamide
CAS Number
1979939-16-6
Molecular Formula
C25H22ClF3N4O2
Formula Weight
502.9
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/mL
- DMSO: 16 mg/mL
- Ethanol: 5 mg/mL
SMILES
O=C(N[C@@H](C)C1=CC=C(Cl)C=C1)CCC2=NC3=CC=CN=C3N2CC4=CC=C(OC(F)(F)F)C=C4
InChi Code
InChI=1S/C25H22ClF3N4O2/c1-16(18-6-8-19(26)9-7-18)31-23(34)13-12-22-32-21-3-2-14-30-24(21)33(22)15-17-4-10-20(11-5-17)35-25(27,28)29/h2-11,14,16H,12-13,15H2,1H3,(H,31,34)/t16-/m0/s1
InChi Key
HXYXHSDYBDFOFO-INIZCTEOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-20904-25 |
|---|---|
| Supplier Part Number | 20904-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1979939-16-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |