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Cayman HC-067047
List Price
$36.00
Your Price
$36.00
Cayman HC-067047 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-20927-1
MFG.PART:
20927-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
HC-067047 is a TRPV4 antagonist that reversibly inhibits currents through human, rat, and mouse TRPV4 orthologs (IC50s = 48, 133, and 17 nM, respectively). It is selective for TRPV4 over TRPV1, TRPV2, TRPV3, and TRPM8 channels. HC-067047 has been shown to increase functional bladder capacity and to reduce micturition frequency in wild-type mice and rats with cystitis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-methyl-1-[3
CAS Number
883031-03-6
Molecular Formula
C26H28F3N3O2
Formula Weight
471.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMF:PBS(pH7.2) (1:2): 0.33 mg/mL
- DMSO: 15 mg/mL
- Ethanol: 1 mg/mL
λmax
279 nm
SMILES
CC1=C(C(NC2=CC=CC(C(F)(F)F)=C2)=O)C=C(C3=CC=CC=C3)N1CCCN4CCOCC4
InChi Code
InChI=1S/C26H28F3N3O2/c1-19-23(25(33)30-22-10-5-9-21(17-22)26(27,28)29)18-24(20-7-3-2-4-8-20)32(19)12-6-11-31-13-15-34-16-14-31/h2-5,7-10,17-18H,6,11-16H2,1H3,(H,30,33)
InChi Key
NCZYSQOTAYFTNM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-20927-1 |
|---|---|
| Supplier Part Number | 20927-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 883031-03-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |