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Cayman Deoxyarbutin
List Price $238.00 Your Price $238.00
Cayman Deoxyarbutin - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-21077-50
MFG.PART: 21077-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Deoxyarbutin is a tyrosinase inhibitor (IC50 = 17.5 μM for mushroom tyrosinase).1 It reduces melanin content in isolated dark human melanocytes when used at a concentration of 1.56 μM.2 Topical administration of deoxyarbutin (5%) induces skin lightening in human skin mouse xenograft models. Deoxyarbutin also inhibits proliferation of B16/F10 murine melanoma cells (EC50 = 39.56 μM).3 It induces apoptosis and halts the cell cycle at the S phase in B16/F10 cells when used at a concentration of 50 μM. Deoxyarbutin (50 mg/kg) reduces tumor growth in a B16/F10 murine melanoma model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[(tetrahydro-
CAS Number
53936-56-4
Molecular Formula
C11H14O3
Formula Weight
194.2
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 10 mg/mL
- Ethanol: 25 mg/mL
- Ethanol:PBS (pH 7.2) (1:20): 0.04 mg/mL
λmax
225, 289 nm
SMILES
OC1=CC=C(OC2OCCCC2)C=C1
InChi Code
InChI=1S/C11H14O3/c12-9-4-6-10(7-5-9)14-11-3-1-2-8-13-11/h4-7,11-12H,1-3,8H2
InChi Key
GFBCWCDNXDKFRH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
4°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21077-50 |
|---|---|
| Supplier Part Number | 21077-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | 4 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 53936-56-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |