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Cayman RU-SKI 201 (hydrochloride)
List Price
$291.00
Your Price
$291.00
Cayman RU-SKI 201 (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21101-5
MFG.PART:
21101-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
RU-SKI 201 is an inhibitor of hedgehog acyltransferase (Hhat; IC50 = 0.2 μM for recombinant enzyme).1 It inhibits palmitoylation of sonic hedgehog (Shh) in Shh-overexpressing HEK293 cells with a tagging IC50 (TC50) value of 0.87 μM. RU-SKI 201 inhibits hedgehog (Hh) signaling in H520, PANC-1, and MCF-7 cancer cells co-cultured with Shh-Light2 cells (IC50s = 4.8, 7.8, and 8.5 μM, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[6,7-dihy
CAS Number
2320262-09-5
Molecular Formula
C20H27N3OS • 2HCl
Formula Weight
430.4
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
λmax
203, 266 nm
SMILES
CCC(C)CNCC(N1CCC2=C(C=CS2)C1C3=NC(C)=CC=C3)=O.Cl.Cl
InChi Code
InChI=1S/C20H27N3OS.2ClH/c1-4-14(2)12-21-13-19(24)23-10-8-18-16(9-11-25-18)20(23)17-7-5-6-15(3)22-17;;/h5-7,9,11,14,20-21H,4,8,10,12-13H2,1-3H3;2*1H
InChi Key
TUDOZEOETHEGCR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21101-5 |
|---|---|
| Supplier Part Number | 21101-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2320262-09-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |