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Cayman Leukotriene B5
List Price $291.00 Your Price $291.00
Cayman Leukotriene B5 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-21110-50
MFG.PART: 21110-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Leukotriene B5 (LTB5) is a leukotriene with diverse biological activities.1,2,3,4,5 It is a metabolite of eicosapentaenoic acid (EPA; Item Nos. 90110 | 90110.1 | 21908) formed through the 5-lipoxygenase (5-LO) pathway.6 LTB5 increases contraction of bullfrog lung strips ex vivo in a concentration-dependent manner.1 In vivo, LTB5 (100 nM) reduces tumor volume in mice injected with Tm1 murine melanoma cells.2 LTB5 also elicits chemokinesis and lysosomal enzyme release from polymorphonuclear leukocytes (PMNLs) 20- to 30-fold less, and induces platelet aggregation 8-fold less, potently than LTB4 (Item No. 20110).3,4,5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5S,12R-dihy
CAS Number
80445-66-5
Synonyms
- LTB5
Molecular Formula
C20H30O4
Formula Weight
334.5
Purity
≥98%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- DMF: >50 mg/mL
- DMSO: >50 mg/mL
- Ethanol: >50 mg/mL
- PBS pH 7.2: >1 mg/mL
λmax
271 nm
SMILES
CC/C=C\C/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O
InChi Code
InChI=1S/C20H30O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h3-4,6-11,14-15,18-19,21-22H,2,5,12-13,16-17H2,1H3,(H,23,24)/b4-3-,8-7+,9-6-,14-10+,15-11-/t18-,19-/m1/s1
InChi Key
BISQPGCQOHLHQK-HDNPQISLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-21110-50 |
|---|---|
| Supplier Part Number | 21110-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 80445-66-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |