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Cayman TASIN-1
List Price
$255.00
Your Price
$255.00
Cayman TASIN-1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21155-1
MFG.PART:
21155-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
TASIN-1 is a small molecule inhibitor that specifically kills cells with adenomatous polyposis coli (APC) truncations (IC50 = 70 nM) but spares cells with wild-type APC. TASIN-1 is effective in vivo, inhibiting tumor growth of colorectal cancer (CRC) cells with truncated APC, but not wild-type CRC cells, in a mouse xenograft model. TASIN-1 decreases cholesterol biosynthesis in APC-truncated cells but not in wild-type APC cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[(4-meth oxyphenyl)sul fonyl]-4-meth yl-1,4-bipi peridine
CAS Number
792927-06-1
Molecular Formula
C18H28N2O3S
Formula Weight
352.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMF:PBS (pH 7.2) (1:4): 0.2 mg/mL
- DMSO: 15 mg/mL
- Ethanol: 25 mg/mL
λmax
241 nm
SMILES
CC1CCN(C2CCN(S(C3=CC=C(OC)C=C3)(=O)=O)CC2)CC1
InChi Code
InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)16-9-13-20(14-10-16)24(21,22)18-5-3-17(23-2)4-6-18/h3-6,15-16H,7-14H2,1-2H3
InChi Key
XCBHYDPDIJQQGM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21155-1 |
|---|---|
| Supplier Part Number | 21155-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 792927-06-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |