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Cayman POM 1
List Price $94.00 Your Price $94.00
Cayman POM 1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-21160-10
MFG.PART: 21160-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
POM 1 is a polyoxometalate that inhibits ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) 1 and 3 with Ki values of 2.58 and 3.26 µM, respectively. It demonstrates 10-fold lower inhibitory activity for NTPDase 2 (Ki = 28.8 µM) and does not inhibit P2Y12 receptors (Ki > 10 µM). Inhibition of ecto-NTPDases that are capable of hydrolyzing nucleoside tri- and diphosphates (i.e., ATP, ADP, UTP, or UDP) can result in a potentiation of purinergic signaling due to an increase in the extracellular nucleotide concentrations. This subtype-selective NTPase inhibitor has been used to investigate the mechanisms of purinergic signaling.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
tungstate (W12(OH)2O38
CAS Number
314075-43-9
Synonyms
- Sodium Metatung
state - Sodium Polyoxotung
state
Molecular Formula
H2O40W12 • H2O • 6Na
Formula Weight
3004.0
Formulation
A crystalline solid
Solubility
- DMF: 0.12 mg/mL
- DMSO: 0.16 mg/mL
- PBS (pH 7.2): 3 mg/mL
SMILES
O=[W+4]([O-2]1)([O-2][W+4]([OH-]2[W+4]34([O-2]5)([O-2]6)=O)([O-2]3)([O-2]7)([O-2]8)=O)([O-2][W+4]9%10([O-2][W+4]%11%12([O-2]%13)([O-2]%14)=O)([O-2][W+4]%15%16%14([O-2]%17)=O)=O)([O-2][W+4]8([O-2]%15[W+4]%18%176([O-2]%19)=O)([O-2]%18)([O-2]%16)=O)[OH-]9[W+4]1([O-2][W+4]([O-2]%11[W+4]%20%135%19=O)([O-2]%20)([O-2]%12)([O-2]%21)=O)([O-2][W+4]27%21([O-2]4)=O)([O-2]%10)=O.[Na+].O.[Na+].[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/6Na.3H2O.38O.12W/H;;;;;;3*1H2;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/q6*+1;;;;;;;;;;;;;;;;26*-2;12*+4/p-2
InChi Key
VBYQPULVKQWCQY-UHFFFAOYSA-L
Shipping & Storage Information
Storage
Room temperature
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21160-10 |
|---|---|
| Supplier Part Number | 21160-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | 22 |
| Refrigerated-Frozen | N |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 314075-43-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |