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Cayman Gly-Pro-pNA (hydrochloride)
List Price $43.00 Your Price $43.00
Cayman Gly-Pro-pNA (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-21244-10
MFG.PART: 21244-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Gly-Pro-pNA is a chromogenic substrate that can be cleaved by the circulating enzyme, dipeptidyl peptidase IV (DPP IV). Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm. DPP IV inactivates the two peptides responsible for a majority of nutrient-stimulated insulin secretion: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1). This substrate can be used to screen for DPP IV inhibitors, which have emerged as a new class of experimental antidiabetic agents.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
glycyl-N-(4-
CAS Number
103213-34-9
Synonyms
- Gly-Pro p-
nitroanilide - GP-pNA
Molecular Formula
C13H16N4O4 • HCl
Formula Weight
328.8
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- PBS (pH 7.2): 10 mg/mL
λmax
221, 312 nm
SMILES
O=C(CN)N1CCC[C@H]1C(NC2=CC=C([N+]([O-])=O)C=C2)=O.Cl
InChi Code
InChI=1S/C13H16N4O4.ClH/c14-8-12(18)16-7-1-2-11(16)13(19)15-9-3-5-10(6-4-9)17(20)21;/h3-6,11H,1-2,7-8,14H2,(H,15,19);1H/t11-;/m0./s1
InChi Key
VBBFIBMVFSUUBP-MERQFXBCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21244-10 |
|---|---|
| Supplier Part Number | 21244-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 103213-34-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |