Cayman Vinorelbine (tartrate)

Name: Cayman Vinorelbine (tartrate)
SKU: CAYM-21262-25
Price: 233.00 USD

List Price $233.00 Your Price $233.00

Cayman Vinorelbine (tartrate) - CAYM (Additional S&H Or Hazmat Fees May Apply)

NETA PART: CAYM-21262-25

MFG.PART: 21262-25

UNSPSC: 12352200

Manufacturer: Cayman

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Description

Product Description

Vinorelbine is a semisynthetic vinca alkaloid with microtubule destabilizing activity.^1,2 It inhibits microtubule polymerization and blocks mitosis at the metaphase/anaphase transition, preventing HeLa cell proliferation with an IC₅₀ value of 1.25 nM.³ In in vitro and in vivo models, vinorelbine has demonstrated additive effects when combined with other antimitotic agents to reduce the proliferation of various solid tumor, lymphoma, or lung cancer cell lines.¹

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

(2β,3β,4β,5α,12R,19α)-4-(acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic acid, methyl ester, 2R,3R-dihydroxybutanedioate (1:2)

CAS Number

125317-39-7

Synonyms

KW 2307

Molecular Formula

C₄₅H₅₄N₄O₈ • 2C₄H₆O₆

Formula Weight

1079.1

Purity

≥95%

Formulation(Request formulation change)

A crystalline solid

Solubility(Learn about Variance in Solubility)

DMSO: 46 mg/mL
Water: 10 mg/mL

λ_max

214, 269, 313 nm

SMILES

[H][C@@]1([C@](C(OC)=O)(O)[C@H](OC(C)=O)[C@@]2(C=CCN3CC[C@]41[C@@]32[H])CC)N(C)C5=C4C=C([C@@]6(C(OC)=O)C[C@]7([H])C=C(CC)C[N@@](C7)CC8=C6NC9=C8C=CC=C9)C(OC)=C5.O[C@H]([C@H](C(O)=O)O)C(O)=O.O[C@H]([C@H](C(O)=O)O)C(O)=O

InChi Code

InChI=1S/C45H54N4O8.2C4H6O6/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7;2*5-1(3(7)8)2(6)4(9)10/h10-15,19

InChi Key

CILBMBUYJCWATM-PYGJLNRPSA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Wet ice in continental US; may vary elsewhere

Stability

≥ 4 years

Specifications

More Information
SKU	CAYM-21262-25
Supplier Part Number	21262-25
UM	EA
UNSPSC	12352200
Manufacturer	Cayman
MSDS URL	Click here
Temperature	-20
Refrigerated-Frozen	Y
CountryOfOrigin	China
ProductLine	CAYM
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	5
Hazardous	Y
CAS Number	125317-39-7
Energy Star	No
Green	No
Controlled	N

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NETA PART NO.	Quantity

Cayman Vinorelbine (tartrate)

Product Description

Technical Information

Shipping & Storage Information

Product Title