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Cayman BYK204165
List Price $157.00 Your Price $157.00
Cayman BYK204165 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-21430-5
MFG.PART: 21430-5
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
BYK204165 is a selective inhibitor of poly(ADP-ribose) polymerase 1 (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay).1 It is selective for PARP1 over PARP2 (IC50 = 4,168 nM for murine PARP2 in an enzyme assay). BYK204165 inhibits hydrogen peroxide-activated PARP in A549 human lung epithelial, C4I human cervical, and H9c2 rat cardiac myoblast cells with IC50 values of 229.09, 1,778.28, and 123.03 nM, respectively.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[(1-methyl-
CAS Number
1104546-89-5
Synonyms
- PARP Inhibitor XIV
Molecular Formula
C15H12N2O2
Formula Weight
252.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 10 mg/mL
λmax
427 nm
SMILES
O=C1NC(C(C=CC=C2)=C2/C1=C\C3=CC=CN3C)=O
InChi Code
InChI=1S/C15H12N2O2/c1-17-8-4-5-10(17)9-13-11-6-2-3-7-12(11)14(18)16-15(13)19/h2-9H,1H3,(H,16,18,19)/b13-9+
InChi Key
BTYSIDSTHDDAJW-UKTHLTGXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21430-5 |
|---|---|
| Supplier Part Number | 21430-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1104546-89-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |