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Cayman Y-26763
List Price $41.00 Your Price $41.00
Cayman Y-26763 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-21459-1
MFG.PART: 21459-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Y-26763 is an activator of ATP-sensitive potassium (KATP) channels. It increases the frequency of KATP channel openings in the presence of ATP and activates KATP channel currents in isolated human β-cells when used at a concentration of 200 μM. It also inhibits increases in intracellular calcium induced by histamine or norepinephrine (Item No. ) in isolated rabbit mesenteric artery smooth muscle in a concentration-dependent manner. Y-26763 induces relaxation in isolated precontracted rat aortic rings (IC50 = 0.027 μM). It decreases mean blood pressure in spontaneously hypertensive rats when administered intravenously at a dose of 0.03 mg/kg, an effect that can be reversed by glibenclamide (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(3S,4R)-6-
CAS Number
127408-31-5
Molecular Formula
C14H16N2O4
Formula Weight
276.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: 100 mm
- Ethanol: 100 mm
λmax
253, 290 nm
SMILES
O[C@H]1[C@H](N(C(C)=O)O)C2=CC(C#N)=CC=C2OC1(C)C
InChi Code
InChI=1S/C14H16N2O4/c1-8(17)16(19)12-10-6-9(7-15)4-5-11(10)20-14(2,3)13(12)18/h4-6,12-13,18-19H,1-3H3/t12-,13+/m1/s1
InChi Key
IWTCFIIOUXJOOV-OLZOCXBDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21459-1 |
|---|---|
| Supplier Part Number | 21459-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 127408-31-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |