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Cayman Sulfadoxin
List Price $312.00 Your Price $312.00
Cayman Sulfadoxin - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-21488-50
MFG.PART: 21488-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Sulfadoxin is a sulfonamide antibiotic that inhibits dihydropteroate synthetase (DHPS), an enzyme involved in folic acid (Item No. 20515) synthesis.1 Sulfadoxin competes with 4-aminobenzoate (PABA), the native substrate of DHPS, and inhibits PABA incorporation into folic acid.2 Folate is essential for purine and pyrimidine synthesis, therefore, sulfadoxin has antiproliferative activity in non-resistant P. falciparum.2,3 Sulfadoxin inhibits growth of P. falciparum in vitro, but potency varies between non-resistant (IC50 = 4 ng/mL) and resistant strains (IC50 = 3,970 ng/mL).3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-amino-N-(5,6-
CAS Number
2447-57-6
Synonyms
- Ro 4-4393
Molecular Formula
C12H14N4O4S
Formula Weight
310.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 50 mg/mL
- DMSO: 50 mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
- Ethanol: 0.3 mg/mL
λmax
273 nm
SMILES
NC1=CC=C(S(N(C2=NC=NC(OC)=C2OC)[H])(=O)=O)C=C1
InChi Code
InChI=1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChi Key
PJSFRIWCGOHTNF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21488-50 |
|---|---|
| Supplier Part Number | 21488-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 2447-57-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |