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Cayman NLG-919 analog
List Price
$41.00
Your Price
$41.00
Cayman NLG-919 analog - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21509-1
MFG.PART:
21509-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
(±)-NLG-919 is an indoleamine 2,3-dioxygenase (IDO) pathway inhibitor (Ki = 7 nM; EC50 = 75 nM). (±)-NLG-919 inhibits IDO-induced T cell suppression and restores T cell response during allogenic mixed lymphocyte reactions in vitro (ED50s = 80 and 120 nM, respectively). In vivo, (±)-NLG-919 induces a 95% reduction in tumor volume when administered in conjunction with a pmel-1 T cell vaccine.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
α-cyclohexyl-
CAS Number
1402836-58-1
Synonyms
- GDC-0919
Molecular Formula
C18H22N2O
Formula Weight
282.4
Purity
≥98% (mixture of enantiomers)
Formulation
A crystalline solid
Solubility
- DMF: 16 mg/mL
- DMSO: 16 mg/mL
- DMSO:PBS (pH 7.2) (1:10): 0.3 mg/mL
- Ethanol: 14 mg/mL
λmax
213, 274 nm
SMILES
OC(C1CCCCC1)CC2N3C(C4=CC=CC=C42)=CN=C3
InChi Code
InChI=1S/C18H22N2O/c21-18(13-6-2-1-3-7-13)10-16-14-8-4-5-9-15(14)17-11-19-12-20(16)17/h4-5,8-9,11-13,16,18,21H,1-3,6-7,10H2
InChi Key
YTRRAUACYORZLX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21509-1 |
|---|---|
| Supplier Part Number | 21509-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1402836-58-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |