We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman RSM-932A
List Price
$32.00
Your Price
$32.00
Cayman RSM-932A - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21518-1
MFG.PART:
21518-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
RSM-932A is a selective inhibitor of choline kinase α (CHOKα; IC50s = 1 and >50 μM for CHOKα and β, respectively). It induces apoptosis via CHOP signaling and endoplasmic reticulum (ER) stress in MDA-MB-231, MCF-7, SW620, and H460 cancer cells, but it only induces cell cycle arrest and not apoptosis in NCM460 and MCF-10A normal epithelial cells. RSM-932A inhibits the growth of HT-29 colon cancer cells in vitro (IC50 = 1.15 μM) and in vivo in a mouse xenograft model (ED50 = 7.5 mg/kg).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,1-[[[1,1-
CAS Number
850807-63-5
Molecular Formula
C46H38Cl2N4 • 2Br
Formula Weight
877.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMSO: 3 mg/mL
- DMSO:PBS (pH 7.2)(1:5): 0.16 mg/mL
λmax
233, 255, 364 nm
SMILES
ClC1=CC=C(N(C2=CC=[N+](CC3=CC=C(C4=CC=C(C[N+]5=C(C=CC=C6)C6=C(N(C7=CC=C(Cl)C=C7)C)C=C5)C=C4)C=C3)C8=C2C=CC=C8)C)C=C1.[Br-].[Br-]
InChi Code
InChI=1S/C46H38Cl2N4.2BrH/c1-49(39-23-19-37(47)20-24-39)43-27-29-51(45-9-5-3-7-41(43)45)31-33-11-15-35(16-12-33)36-17-13-34(14-18-36)32-52-30-28-44(42-8-4-6-10-46(42)52)50(2)40-25-21-38(48)22-26-40;;/h3-30H,31-32H2,1-2H3;2*1H/q+2;;/p-2
InChi Key
DGBVSSXGHKAASQ-UHFFFAOYSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21518-1 |
|---|---|
| Supplier Part Number | 21518-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 850807-63-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |