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Cayman Bicyclol


Product Description
Bicyclol is a hepatoprotective agent.1,2,3,4 It has antiviral activity against hepatitis B (HBV), reducing viral DNA and the secretion of the HBV antigens HBsAg and HBeAg by 59 and 35%, respectively, in infected 2.2.15 HepG2 cells.1 In vivo, bicyclol reduces duck HBV (DHBV) DNA in DHBV-infected ducks at doses ≥0.4 g/kg. It also reduces the expression of TNF-α and the accumulation of lymphocytes in the liver in a mouse model of liver injury induced by concanavalin A (Item No. 14951).2 Oral administration of bicyclol prior to injection of diethylnitrosamine (DEN) and phenobarbital (PB; Item Nos. 9001494 | 20987) prevents formation of DEN/PB-induced hepatocellular carcinomas.3 It also reduces liver fibrosis in a rat model of bile duct ligation-induced hepatic fibrosis.4
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 25 mg/mL
- DMSO: 25 mg/mL
- DMSO:PBS (pH 7.2)(1:9): 0.1 mg/mL
Shipping & Storage Information
| SKU | CAYM-21551-5 |
|---|---|
| Supplier Part Number | 21551-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 118159-48-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |

