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Cayman GTS-21 (hydrochloride)
List Price $125.00 Your Price $125.00
Cayman GTS-21 (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-21570-10
MFG.PART: 21570-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
GTS-21 is an agonist of α7-containing nicotinic acetylcholine receptors (nAChRs) that, at a concentration of 100 μM, activates human α7-containing nAChRs expressed in Xenopus oocytes to 60% of the levels generated by endogenous ligand acetylcholine. It is selective for α7-containing nAChRs, having no activity at α2-, α3-, and α4-containing nAChRs at a concentration of 100 μM. GTS-21 stimulates dopamine release from rat striatal slices (EC50 = 10 μM). In vivo, GTS-21 decreases delay in the delayed matching-to-sample task in monkeys. It also suppresses amnesia and neuronal cell death in a gerbil model of ischemia-reperfusion injury.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3E)-3-[(2,4-
CAS Number
156223-05-1
Synonyms
- DMXB-A
Molecular Formula
C19H20N2O2 • 2HCl
Formula Weight
381.3
Purity
≥98%
Formulation
A solid
Solubility
- DMF: 1 mg/mL
- DMSO: 2 mg/mL
- Ethanol: 1 mg/mL
- PBS (pH 7.2): 10 mg/mL
λmax
258, 406 nm
SMILES
COC1=C(/C=C2CCCN=C\2C3=CN=CC=C3)C=CC(OC)=C1.Cl.Cl
InChi Code
InChI=1S/C19H20N2O2.2ClH/c1-22-17-8-7-14(18(12-17)23-2)11-15-5-4-10-21-19(15)16-6-3-9-20-13-16;;/h3,6-9,11-13H,4-5,10H2,1-2H3;2*1H/b15-11+;;
InChi Key
BXKYFUGAAFLYJL-BXGYHSFXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21570-10 |
|---|---|
| Supplier Part Number | 21570-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 156223-05-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |