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Cayman RP-8-bromo-Cyclic AMPS (sodium salt)
List Price
$193.00
Your Price
$193.00
Cayman RP-8-bromo-Cyclic AMPS (sodium salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21584-500
MFG.PART:
21584-500
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
RP-8-bromo-Cyclic AMPS (RP-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP.1,2 It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. RP-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
8-bromo-
CAS Number
925456-59-3
Synonyms
- 8-Bromo
adenosine 3,5-cyclic monophosphoro thioate, RP-isomer - RP-8-Br-
cAMPS - RP-8-bromo-
cAMPS
Molecular Formula
C10H10BrN5O5PS • Na
Formula Weight
446.2
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 25 mg/mL
- Ethanol: 0.5 mg/mL
- PBS (pH 7.2): 10 mg/mL
λmax
212, 263 nm
SMILES
O[C@H]1[C@H](N2C(Br)=NC3=C2N=CN=C3N)O[C@H]4[C@H]1O[P@@](OC4)([S-])=O.[Na+]
InChi Code
InChI=1S/C10H11BrN5O5PS.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(20-9)1-19-22(18,23)21-6;/h2-3,5-6,9,17H,1H2,(H,18,23)(H2,12,13,14);/q;+1/p-1/t3-,5-,6-,9-,22-;/m1./s1
InChi Key
SKJLJCVVXRNYGJ-FBGJTXKBSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21584-500 |
|---|---|
| Supplier Part Number | 21584-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Germany |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 925456-59-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |