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Cayman ZLN024
List Price $655.00 Your Price $655.00
Cayman ZLN024 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-21644-50
MFG.PART: 21644-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
ZLN024 is an allosteric activator of AMP-activated protein kinase (AMPK) heterotrimers (EC50s = 0.42 and 0.95 µM for α1β1γ1 and α2β1γ1, respectively).1 Activation of AMPK by ZLN024 requires phosphorylation of AMPK on Thr172, and ZLN024 protects Thr172 from dephosphorylation by protein phosphatase 2Cα.1 ZLN024 stimulates glucose uptake and fatty acid oxidation in L6 myotubes. In primary hepatocytes, ZLN024 decreases fatty acid synthesis and glucose output.1 ZLN024 reduces liver triacylglycerol and total cholesterol content and improves glucose tolerance in db/db mice.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[2-(2-
CAS Number
723249-01-2
Molecular Formula
C13H13BrN2OS
Formula Weight
325.2
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMF:PBS (pH 7.2) (1:4): 0.2 mg/mL
- DMSO: 25 mg/mL
- Ethanol: 5 mg/mL
λmax
249, 282 nm
SMILES
CC1=CC(Br)=C(OCCSC2=NC=CC=N2)C=C1
InChi Code
InChI=1S/C13H13BrN2OS/c1-10-3-4-12(11(14)9-10)17-7-8-18-13-15-5-2-6-16-13/h2-6,9H,7-8H2,1H3
InChi Key
KWJRSHZSULRJHE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21644-50 |
|---|---|
| Supplier Part Number | 21644-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 723249-01-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |