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Cayman 9-cis Retinal
List Price
$54.00
Your Price
$54.00
Cayman 9-cis Retinal - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21692-1
MFG.PART:
21692-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
9-cis Retinal is a natural retinoid that is produced by oxidation of 9-cis retinol by cis-retinol dehydrogenase (cRDH). It binds to cellular retinol-binding protein-I (CRBP-I) and CRBP-II (Kds = 8 and 5 nM, respectively) and to cellular retinaldehyde-binding protein (CRALBP; Kd = 53.3 nM)., In vitro, 9-cis retinal inhibits differentiation of RCJ C5.18 chondrogenic cells into cartilage (IC50 = 8 nM). In vivo, it rescues cone electroretinogram (ERG) responses in Irbp-/- mice, which lack interphotoreceptor retinoid-binding protein and have diminished cone responses, when administered at a dose of 0.375 mg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
9-cis-
CAS Number
514-85-2
Synonyms
- 9-cis Retinaldehyde
- 9-cis Vitamin A aldehyde
Molecular Formula
C20H28O
Formula Weight
284.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- Chloroform: 10 mg/mL
- DMF: 25 mg/mL
- DMSO: 16 mg/mL
- Ethanol: 25 mg/mL
- Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
λmax
373 nm
SMILES
CC1=C(/C=C/C(C)=C\C=C\C(C)=C\C([H])=O)C(C)(C)CCC1
InChi Code
InChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8-,17-13+
InChi Key
NCYCYZXNIZJOKI-MKOSUFFBSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-21692-1 |
|---|---|
| Supplier Part Number | 21692-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -80 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 514-85-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |