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Cayman Pitavastatin lactone
List Price
$63.00
Your Price
$63.00
Cayman Pitavastatin lactone - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21785-1
MFG.PART:
21785-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Pitavastatin lactone is a major phase 2 metabolite of the HMG-CoA reductase inhibitor pitavastatin (Item No. )., Pitavastatin lactone is formed when pitavastatin undergoes glucuronidation by the UDP-glucuronysyltransferase (UGT) isoforms UGT1A1, UGT1A3, or UGT2B7 to form pitavastatin glucuronide, which then undergoes non-enzymatic conversion to pitavastatin lactone. It can be retroconverted to pitavastatin via hydrolysis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6S- [(1E)-2-[2- cyclopropyl- 4-(4- fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro- 4R-hydroxy- 2H-pyran-2- one
CAS Number
141750-63-2
Molecular Formula
C25H22FNO3
Formula Weight
403.5
Purity
≥98%
Formulation
A solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS(pH 7.2) (1:3): 0.25 mg/mL
- Ethanol: 10 mg/mL
SMILES
FC(C=C1)=CC=C1C2=C(/C=C/[C@H]3OC(C[C@H](O)C3)=O)C(C4CC4)=NC5=C2C=CC=C5
InChi Code
InChI=1S/C25H22FNO3/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-19-13-18(28)14-23(29)30-19/h1-4,7-12,16,18-19,28H,5-6,13-14H2/b12-11+/t18-,19-/m1/s1
InChi Key
XJVKVAFYQRWVAJ-MCBHFWOFSA-N
Shipping & Storage Information
Storage
4°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21785-1 |
|---|---|
| Supplier Part Number | 21785-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | 4 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 141750-63-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |