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Cayman KIN1408
List Price
$194.00
Your Price
$194.00
Cayman KIN1408 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21790-10
MFG.PART:
21790-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
KIN1408 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity. It induces interferon regulatory factor 3 (IRF3) activation and translocation into the nucleus in a concentration-dependent manner in HEK293 cells without inducing cellular toxicity. KIN1408 induces expression of the innate immune genes MDA5, RIG-1, Mx1, IRF7, and IFIT1 in THP-1 cells stimulated with phorbol 12-myristate 12-acetate (PMA; Item No. ). It exhibits concentration-dependent broad-spectrum antiviral activity against dengue virus 2 as well as the influenza A, Ebola, Nipah, and Lassa viruses.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7-[[4-
CAS Number
1903800-11-2
Molecular Formula
C25H19F2N3O3S
Formula Weight
479.5
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: 30 mg/mL
λmax
247, 302, 309 nm
SMILES
FC(F)OC1=CC=C(C(C2=C(O)C(N=CC=C3)=C3C=C2)N(C4=NC(C=C(OC)C=C5)=C5S4)[H])C=C1
InChi Code
InChI=1S/C25H19F2N3O3S/c1-32-17-9-11-20-19(13-17)29-25(34-20)30-21(15-4-7-16(8-5-15)33-24(26)27)18-10-6-14-3-2-12-28-22(14)23(18)31/h2-13,21,24,31H,1H3,(H,29,30)
InChi Key
YSGBFDHVEQJPPX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21790-10 |
|---|---|
| Supplier Part Number | 21790-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1903800-11-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |