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Cayman SR 202
List Price
$50.00
Your Price
$50.00
Cayman SR 202 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21846-1
MFG.PART:
21846-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
SR 202 is an antagonist of peroxisome proliferator-activated receptor γ (PPARγ) transcriptional activity induced by troglitazone (Item No. ; IC50 = 140 µM) but not of basal PPARγ activity. It is selective for PPARγ, not affecting basal or agonist-induced transcriptional activity of PPARα, PPARβ, or the farnesoid X receptor (FXR). It inhibits PPARγ-dependent differentiation of preadipocyte 3T3-L1 cells in a dose-dependent manner. SR 202 (400 mg/kg) decreases the amount of weight gained and white adipose tissue mass accumulated by mice fed a standard or high-fat diet for ten weeks and is associated with lower PPARγ mRNA levels. It protects against high-fat diet-induced insulin resistance in wild-type mice and improves insulin sensitivity in ob/ob mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
phosphoric acid, (4-chlorophenyl)
CAS Number
76541-72-5
Molecular Formula
C11H17ClO7P2
Formula Weight
358.7
Purity
≥95%
Formulation
A crystalline solid
Solubility
- Water: 100 mm
λmax
226 nm
SMILES
ClC1=CC=C(C=C1)C(OP(OC)(OC)=O)P(OC)(OC)=O
InChi Code
InChI=1S/C11H17ClO7P2/c1-15-20(13,16-2)11(19-21(14,17-3)18-4)9-5-7-10(12)8-6-9/h5-8,11H,1-4H3
InChi Key
VQHUQHAPWMNBLP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21846-1 |
|---|---|
| Supplier Part Number | 21846-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 76541-72-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |