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Cayman LYG-202
List Price
$128.00
Your Price
$128.00
Cayman LYG-202 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21976-5
MFG.PART:
21976-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
LYG-202 is a synthetic flavonoid with anticancer and anti-angiogenic activities.1,2 It inhibits proliferation of HepG2, MCF-7, HeLa, BGC-823, MDA-MB-435, and HCT116 cancer cells in vitro (IC50s = 4.74-27.70 μM) via induction of apoptosis and dissipation of the mitochondrial membrane potential.1 LYG-202 reduces tumor growth in S180 sarcoma cell-inoculated mice. It also inhibits VEGF-stimulated human umbilical vein endothelial cells (HUVEC) cell migration and tube formation in vitro and decreases capillary sprouting in isolated rat aortic rings and the chicken chorioallantoic membrane (CAM) model of angiogenesis.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-hydroxy-8-
CAS Number
1175077-25-4
Molecular Formula
C25H30N2O5
Formula Weight
438.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 14 mg/mL
- DMF:PBS (pH7.2) (1:40): 0.12 mg/mL
- Ethanol: 2.5 mg/mL
λmax
276 nm
SMILES
CN1CCN(CCCCOC2=CC(O)=C(C(C=C(C3=CC=CC=C3)O4)=O)C4=C2OC)CC1
InChi Code
InChI=1S/C25H30N2O5/c1-26-11-13-27(14-12-26)10-6-7-15-31-22-17-20(29)23-19(28)16-21(18-8-4-3-5-9-18)32-25(23)24(22)30-2/h3-5,8-9,16-17,29H,6-7,10-15H2,1-2H3
InChi Key
ICGYSEWPMDWBIL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21976-5 |
|---|---|
| Supplier Part Number | 21976-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 1175077-25-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |