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Cayman 6-hydroxy Bexarotene
List Price
$69.00
Your Price
$69.00
Cayman 6-hydroxy Bexarotene - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22098-1
MFG.PART:
22098-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
6-hydroxy Bexarotene is an oxidative metabolite of bexarotene (Item No. ), a high-affinity ligand for retinoid X receptors (RXRs). 6-hydroxy Bexarotene binds to RXRα, RXRβ, and RXRγ as well as retinoic acid receptor α (RARα; Kds = 3.46, 4.21, 4.83, and 8.17 μM, respectively). It selectively activates RXRα, RXRβ, and RXRγ over RARα, RARβ, and RARγ in vitro (EC50s = 398, 356, 420, 4,414, 2,121, and 2,043 nM, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[1-
CAS Number
368451-07-4
Molecular Formula
C24H28O3
Formula Weight
364.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMF:PBS (pH 7.2)(1:3): 0.25 mg/mL
- DMSO: 10 mg/mL
- Ethanol: 0.5 mg/mL
λmax
204, 264 nm
SMILES
CC(C(C(C1=CC=C(C(O)=O)C=C1)=C)=C2)=CC3=C2C(C)(C)CC(O)C3(C)C
InChi Code
InChI=1S/C24H28O3/c1-14-11-20-19(23(3,4)13-21(25)24(20,5)6)12-18(14)15(2)16-7-9-17(10-8-16)22(26)27/h7-12,21,25H,2,13H2,1,3-6H3,(H,26,27)
InChi Key
WTWGVKDCAJSUBZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22098-1 |
|---|---|
| Supplier Part Number | 22098-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 368451-07-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |