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Cayman TUG-770
List Price
$680.00
Your Price
$680.00
Cayman TUG-770 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22131-25
MFG.PART:
22131-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
TUG-770 is an agonist of free fatty acid receptor 1 (FFA1/GPR40; EC50 = 6.16 nM for a response to the full FFA1 agonist TUG-20 in a calcium assay in 1311N1 cells).1 It is selective for FFA1 over FFA2 (EC50 = 933 nM in a BRET assay). It reduces glucose levels in mice in an intraperitoneal glucose tolerance test in a dose-dependent manner with a maximal reduction at a dose of 50 mg/kg. It also reduces glucose levels in an oral glucose tolerance test in a diet-induced obesity mouse model for at least 29 days.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[2-[2-
CAS Number
1402601-82-4
Molecular Formula
C19H14FNO2
Formula Weight
307.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 10 mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
- Ethanol: 1 mg/mL
λmax
203, 285 nm
SMILES
OC(CCC1=C(F)C=C(C#CC2=C(CC#N)C=CC=C2)C=C1)=O
InChi Code
InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
InChi Key
KIZUBVPJNPVIIN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22131-25 |
|---|---|
| Supplier Part Number | 22131-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1402601-82-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |