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Cayman CTX-0294885
List Price
$37.00
Your Price
$37.00
Cayman CTX-0294885 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22197-1
MFG.PART:
22197-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
CTX-0294885 is a broad spectrum kinase inhibitor that inhibited FAK, FLT3, JAK2, JAK3, Src, Aurora kinase A, and VEGF receptor 3 (IC50s = 4, 1, 3, 28, 2, 18, and 3 nM, respectively) in an initial screen. In an affinity purification experiment, CTX-0294885 beads bound to kinases from every major group and captured all members of the AKT family of proteins. In a large-scale kinome profiling experiment, it captured 235 kinases from MDA-MB-231 breast cancer cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[5-chloro-
CAS Number
1439934-41-4
Molecular Formula
C22H24ClN7O
Formula Weight
437.9
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMSO: 20 mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
- Ethanol: 0.1 mg/mL
λmax
205, 286 nm
SMILES
O=C(NC)C1=C(NC2=NC(NC3=CC=C(N4CCNCC4)C=C3)=NC=C2Cl)C=CC=C1
InChi Code
InChI=1S/C22H24ClN7O/c1-24-21(31)17-4-2-3-5-19(17)28-20-18(23)14-26-22(29-20)27-15-6-8-16(9-7-15)30-12-10-25-11-13-30/h2-9,14,25H,10-13H2,1H3,(H,24,31)(H2,26,27,28,29)
InChi Key
FCLOIQHNUARDSR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22197-1 |
|---|---|
| Supplier Part Number | 22197-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1439934-41-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |